Why Make This Recipe
Mac and Cheese Meatloaf Casserole is the perfect dish for anyone who loves comfort food. This recipe combines two favorites—macaroni and cheese and meatloaf—into one hearty meal that is sure to please the whole family. It’s not only delicious but also easy to make. You can enjoy the creamy cheese and savory meat in every bite. Perfect for weeknight dinners or family gatherings, this casserole will quickly become a staple in your home.
How to Make Mac and Cheese Meatloaf Casserole
Ingredients
- 1 lb ground beef
- 2 cups uncooked macaroni
- 2 cups shredded cheddar cheese
- 1/2 cup diced onion
- 1/2 cup breadcrumbs
- 1 large egg
- 1/4 cup milk (for meatloaf)
- 2 tbsp butter (for cheese sauce)
- 2 cups milk (for cheese sauce)
- 1 tsp salt
- 1/2 tsp pepper
- 1/2 tsp paprika
- 1/2 tsp dry mustard
- 2 tbsp flour
Directions
- Preheat your oven to 350°F (175°C).
- In a mixing bowl, combine ground beef, onion, breadcrumbs, egg, milk, salt, and pepper. Mix well and press into a greased baking dish.
- Bake the meatloaf for 20 minutes.
- While the meatloaf bakes, cook macaroni according to package directions; drain and set aside.
- For the cheese sauce, melt butter in a saucepan over medium heat. Stir in flour and cook for one minute.
- Gradually whisk in milk until thickened. Season with salt, pepper, paprika, and dry mustard. Stir in shredded cheese until melted.
- Combine cooked macaroni with the cheese sauce and pour over the meatloaf layer. Top with the remaining cheese.
- Bake for an additional 25 minutes or until bubbly.
How to Serve Mac and Cheese Meatloaf Casserole
Serve the Mac and Cheese Meatloaf Casserole hot from the oven. You can garnish it with some fresh parsley for a pop of color. Pair it with a simple green salad or some steamed vegetables for a complete meal. Everyone will love digging into this cheesy, meaty goodness!
How to Store Mac and Cheese Meatloaf Casserole
You can store any leftovers in an airtight container in the refrigerator. It will stay fresh for up to three days. To reheat, simply place portions in the microwave or oven until warmed through.
Tips to Make Mac and Cheese Meatloaf Casserole
- Make sure to cook the macaroni al dente, so it doesn’t get mushy when baking.
- Feel free to add extra spices or herbs to the meat mixture for more flavor.
- You can use different types of cheese if you want to switch things up.
Variation
For a twist on this recipe, try adding vegetables like bell peppers or mushrooms to the meatloaf mixture. You could also layer in some cooked spinach for added nutrition.
FAQs
1. Can I make this casserole in advance?
Yes! You can prepare the meatloaf and cheese sauce ahead of time and assemble the casserole. Just bake it when you’re ready to serve.
2. Is this recipe freezer-friendly?
Yes! You can freeze the casserole before baking. Wrap it tightly in foil and freeze it for up to three months. Bake it straight from the freezer, adding extra time as needed.
3. Can I use turkey instead of beef?
Absolutely! Ground turkey works well in this recipe. Adjust the seasonings to your taste, as turkey is often milder in flavor.

Mac and Cheese Meatloaf Casserole
Ingredients
Method
- Preheat your oven to 350°F (175°C).
- In a mixing bowl, combine ground beef, onion, breadcrumbs, egg, milk, salt, and pepper. Mix well and press into a greased baking dish.
- Bake the meatloaf for 20 minutes.
- While the meatloaf bakes, cook macaroni according to package directions; drain and set aside.
- For the cheese sauce, melt butter in a saucepan over medium heat. Stir in flour and cook for one minute.
- Gradually whisk in milk until thickened. Season with salt, pepper, paprika, and dry mustard. Stir in shredded cheese until melted.
- Combine cooked macaroni with the cheese sauce and pour over the meatloaf layer. Top with the remaining cheese.
- Bake for an additional 25 minutes or until bubbly.